Ingredient type

Botanicals & Herbs

Whole plants, leaves, roots and seeds used in traditional medicine and modern supplements. Quality, dose and standardization matter a lot for this group.

Gotu kola (Centella asiatica) round leaves being gathered by hand in a wet field in South Asia (AI-generated illustration) Gotu kola

Evidence: Limited

Gotu kola is a traditional Asian herb studied for memory and mood. One small trial in older adults was encouraging, but a 2017 meta-analysis found no ...

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Cat's claw (Uncaria tomentosa) woody vine climbing a tree in the Amazon rainforest (AI-generated illustration) Cat’s claw

Evidence: Preliminary

Cat's claw is an Amazonian vine used in traditional medicine. NCCIH says there are very few high quality trials and no conclusive evidence for any hea...

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Soursop (Annona muricata) spiky green fruits on the tree in a tropical orchard (AI-generated illustration) Soursop

Evidence: Preliminary

Soursop is a tropical tree whose leaves are sold as supplements. Evidence is mostly from lab studies, and its compound annonacin has been linked to ne...

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Senna plants with yellow flowers and pods in a sunny field (AI-generated illustration) Senna

Evidence: Strong

Senna is a stimulant laxative that reliably relieves short-term constipation. It does not cause fat loss, and long-term use is linked to cramping, ele...

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Bark from an African cherry (Prunus africana) tree being sustainably harvested in a highland African forest (AI-generated illustration) Pygeum

Evidence: Moderate

Pygeum is an extract from the bark of the African cherry tree. A Cochrane review of 18 small, short trials found it modestly improved urinary symptoms...

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Dong quai (Angelica sinensis) roots being harvested on a mountain farm in China (AI-generated illustration) Dong Quai

Evidence: Preliminary

Dong quai is a Chinese herbal root traditionally used for women's health. It did not outperform placebo for menopausal symptoms in a controlled trial,...

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Eyebright (Euphrasia) small white flowers with purple veins in an alpine meadow, being gathered by hand (AI-generated illustration) Eyebright

Evidence: Preliminary

Eyebright is a small meadow herb used in folk medicine for irritated eyes. Research is limited to cell studies, often of eye drops, and there is no go...

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Purple saffron crocus flowers being picked by hand at dawn (AI-generated illustration) Saffron

Evidence: Moderate

Saffron is the dried stigma of the Crocus sativus flower. It has a moderate body of small trials for low mood, and a limited, mostly Iranian evidence ...

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Large kudzu roots being dug from the soil (AI-generated illustration) Kudzu

Evidence: Preliminary

Kudzu is a climbing vine whose root and flower contain isoflavones. Small human studies of kudzu root extract found people drank less alcohol, but kud...

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