Flavonoids & Polyphenols

Evidence: Preliminary

Quercetin is a plant flavonoid found in onions, apples and tea. It is a strong antioxidant in the lab, but human evidence for eye health is lacking, a...

Evidence: Limited

Bilberry is a European relative of the blueberry, rich in anthocyanins. NCCIH says it has not been clearly shown to help any health condition, and the...

Evidence: Limited

Moro orange extract, sold under the trade name Morosil, comes from a Sicilian blood orange rich in anthocyanins. A few small trials found modest weigh...

Evidence: Preliminary

Apigenin is a chamomile flavonoid with calming effects in animal studies. Human evidence comes mostly from chamomile products and is mixed for insomni...

Evidence: Limited

Pomegranate is rich in polyphenols called ellagitannins. Early prostate studies looked promising, but a placebo-controlled trial found no effect on PS...

Evidence: Limited

Turmeric and its main compound curcumin are widely studied for inflammation. In dentistry, curcumin mouthwashes and gels have shown effects similar to...

Evidence: Moderate

Grape seed extract is rich in proanthocyanidins and has well-controlled studies for cholesterol and blood pressure. Its effect on fasting glucose appe...

Evidence: Limited

Pine bark extract is a polyphenol-rich antioxidant studied in many small trials, including for cognition. Most research uses one branded extract and i...

Evidence: Preliminary

Genistein is a soy isoflavone with weak estrogen-like activity. One small trial in fatty liver patients found improvements in insulin resistance and i...

Evidence: Limited

Chlorogenic acid is the main polyphenol in green coffee beans. Small, often low-quality trials suggest a modest effect on body weight.