Common signs
Feeling tired or low on energy most days, afternoon slumps, needing more effort to keep weight stable, less motivation to exercise, and feeling sluggish after meals.
Common causes
Short or poor-quality sleep, long periods of sitting, loss of muscle with age and inactivity, diets heavy in refined foods and low in protein and fiber, chronic stress, alcohol, and some medications such as antihistamines, sleeping pills and certain blood pressure drugs.
Why energy and metabolism feel harder to manage
Many adults notice that they feel more tired than they used to and that weight creeps up more easily. Part of this is real physiology: muscle mass tends to decline with age and inactivity, and muscle uses more energy than fat even at rest. But much of it comes from everyday habits that slowly drain energy and reduce the calories we burn through movement.
MedlinePlus describes fatigue as a feeling of weariness, tiredness, or lack of energy that is different from simple drowsiness. It is often a normal response to stress, poor sleep or overwork, but it can also be a symptom of a medical problem, which is why persistent fatigue deserves attention rather than a quick fix.
Start with the basics
Protect your sleep. Aim for a consistent bedtime and wake time, a dark and cool bedroom, and limited screens and caffeine late in the day. Short sleep affects appetite hormones as well as energy, and MedlinePlus lists not getting enough sleep among the factors that affect weight gain.
Move more, all day. Structured exercise helps, but so does everyday movement. MedlinePlus notes that even small changes, such as standing instead of sitting while on the phone can burn up to 100 extra calories a day. Taking regular breaks from sitting, walking briskly and choosing stairs all add up.
Build and keep muscle. Resistance training two or more times a week, using body weight, bands or weights, helps maintain the muscle that supports your metabolism as you age.
Eat for steady energy. Meals built around protein, vegetables, fruit, whole grains and healthy fats tend to keep energy steadier than refined snacks and sugary drinks. Drink water through the day.
Manage stress and alcohol. Chronic stress and regular drinking both disrupt sleep and energy. Relaxation techniques, time outdoors and social connection can help.
Set realistic expectations
Changes in energy and body composition usually take weeks to months of consistent habits. It can help to pick one or two changes at a time, such as a fixed bedtime and a daily walk, and track how you feel for a few weeks before adding more. Small, sustainable steps tend to last longer than dramatic overhauls, and they make it easier to see what actually works for you. If you live with a health condition or take medication, ask your doctor which kinds of activity and dietary changes are appropriate before you start.
Where supplements fit
Supplements marketed for “metabolism” or “mitochondria” usually combine antioxidants, adaptogens and stimulant-free botanicals. Some of these ingredients have modest effects on markers like blood pressure or blood sugar in studies, but the NIH Office of Dietary Supplements concludes that the evidence for weight-loss supplements is inconclusive and unconvincing. No capsule can make up for poor sleep or a sedentary routine.
If you want to try a supplement, choose one that discloses exact amounts of each ingredient, check that those amounts resemble what was used in research, and review it with your doctor or pharmacist, particularly if you take medication, are pregnant or breastfeeding, or have a health condition. Most importantly, if tiredness is new, severe or not improving with better habits, get checked rather than self-treating.
When to see a doctor
See a doctor if fatigue lasts more than two weeks despite good sleep and rest, comes with unexplained weight loss or gain, fever, shortness of breath, low mood, heavy periods, or changes in thirst or urination, or if it interferes with daily life. Fatigue can be a sign of anemia, thyroid problems, sleep apnea, diabetes, depression and other conditions that need proper evaluation.
Ingredients studied for this
Amla, or Indian gooseberry, is a sour fruit used in Ayurveda. Small trials suggest improvements in cholesterol, triglycerides and CRP, but t...
Haematococcus is a red microalga and the main natural source of astaxanthin, a carotenoid antioxidant. Trials show mild effects on oxidative...
Maqui berry is a dark purple Chilean fruit rich in anthocyanins. Small human trials suggest effects on oxidative stress markers and after-me...
Rhodiola is an adaptogenic herb promoted for fatigue, stress and performance. Research is mixed and mostly low to moderate quality, with no ...
Schisandra is a berry used in traditional Chinese medicine. A few small trials suggest benefits for muscle strength and menopausal symptoms,...
Cocoa flavanols have the best-studied effect in this formula: a Cochrane review found a small blood pressure reduction. There is no good evi...
Supplements marketed for this
These products are sold with this concern in mind. Our reviews explain what their ingredients can and cannot do.
★★★☆☆
Mitolyn reviewMitolyn is a once-daily capsule with six antioxidant botanicals marketed for mitochondrial fat burning. The ingredients have modest evidence...
